EFFECT OF TP53 DEFICIENCY AND KRAS SIGNALING ON THE BIOENERGETICS OF COLON CANCER CELLS IN RESPONSE TO DIFFERENT SUBSTRATES: A SINGLE CELL STUDY

Effect of TP53 deficiency and KRAS signaling on the bioenergetics of colon cancer cells in response to different substrates: A single cell study

Metabolic reprogramming is a hallmark of cancer.Somatic mutations in genes involved in oncogenic signaling pathways, including KRAS and TP53, rewire the metabolic machinery in cancer cells.We here set out to determine, at the single cell level, metabolic signatures in human colon cancer cells engineered to express combinations of activating KRAS ge

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On Maximum Length Record of the Chub Mackerel (Scomber japonicus Houttuyn, 1782) from Northern Aegean Sea (Turkey, eastern Mediterranean)

The accurate estimates of the maximum Handcream length of fish within a population are significant issues.Because the parameters related to maximum length, weight and age of fish communities in the ecosystem are constantly used in population dynamics and stock estimation studies, recording of such data is vital for determining the life history of f

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Inhibition of biochemical terpene pathways in Achillea millefolium flowers differently affects the behavior of bumblebees (Bombus terrestris) and flies (Lucilia sericata)

Floral scents serve multiple functions in the interactions with organisms.Flowers of Achillea millefolium (Asteraceae) emit scent bouquets dominated by terpenoids.These flowers are mainly visited by flies and beetles, whereas bumblebees, common visitors at other Asteraceae, are absent from A.millefolium flowers.In order to test how a reduced mono-

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